This manual provides facilitator instructions, resources and tools for a four-day workshop to help providers identify and respond to violence against most-at-risk populations, especially men who have sex with men and transgendered individuals. It includes twelve modules: The first five modules contain exercises that sensitize participants to issues of gender and sexuality, stigma, discrimination and gender-based violence,  and the link between these and HIV. Additional modules include an introduction to and practice using the screening tool; best practices in screening; and development of a referral system and safety plans.